Rabbit Anti Human UNC13B Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot,Immunofluorescence) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been purified using Affinity Purified.
More Details:
- Host: Rabbit
- Species: Human,Mouse
- Target: UNC13B
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Recombinant fusion protein of human UNC13B (NP_006368.3).
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
This product can be used in analytical tools such as Western Blot,Immunofluorescence.
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
For research use only.
